Gunslinger Girl

Content:
Simply put, Gunslinger Girl is about hopeless children who are granted another shot at life at the cost of their freedom and innocence. They are given cybernetic implants which enhance their combat capabilities and drugs which impose upon them unquestioning loyalty to their respective masters. Paired with their handlers, they are known as “fratello”, and they must face not only terrorists but the tragedies of the past and the uncertainty of the future as well.

Both very deep and sad animes. Great if you like serious stuff